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We’re Here to Restore What Was Lost.

We believe the body holds the key to healing. While our focus began with short bowel syndrome, our regenerative approach extends to other complex GI conditions affecting the esophagus, colon, and rectum.

Built to Regrow the Intestine. Built to Give Hope.

We are a medical device company on a mission to change how we treat intestinal failure. Inspired by the resilience of the human body and guided by years of surgical innovation and research, we’re developing the first regenerative therapy for patients with Short Bowel Syndrome (SBS).

We’re not just building a device, we’re building a regenerative platform designed to scale across the GI tract and transform how intestinal failure is treated.

Our Vision

A World Where Regeneration Replaces Replacement.

Our vision is bold: a world where intestinal regeneration becomes the new standard of care for Short Bowel Syndrome (SBS) and beyond. We imagine a future where the body’s own tissue can be gently guided to rebuild, restoring health from within.

While our work began in pediatric Short Bowel Syndrome (SBS), the same regenerative principles are now guiding our exploration of solutions for other high-need areas of the GI tract, including the esophagus, colon, and rectum, where healing remains limited and invasive interventions are still the norm.

Clinicians. Innovators. Changemakers.

We are a cross-disciplinary team of physicians, engineers, scientists, and operators, united by the belief that the best solutions come from collaboration and bold thinking. Every one of us is driven by the same goal: to restore health and dignity to those living with SBS.

About

Andre Bessette

CEO, Co-Founder

Vantage Surgical, SentreHeart, PEAK Surgical, ArthroCare

About

James Dunn, MD

PhD Co-Founder

Chief of Pediatric Surgery, Stanford University Former Chief of Pediatric Surgery, UCLA

About

Tom Krummel, MD

Co-Founder

Professor of Surgery, Stanford University Co-Director, Stanford Biodesign Program

About

Michael Helmrath, MD

Advisor

Pediatric Surgeon, Cincinnati Children’s Hospital Professor of Surgery, Cincinnati School of Medicine

About

Mark Puder, MD

Advisor

Professor of Surgery, Harvard Medical School Pediatric Surgeon, Boston Children’s Hospital

About

James Wall, MD

Advisor

Pediatric Surgeon, Stanford University Co-Director, Stanford Biodesign Program

About

Jon A. Vanderhoof, MD

Advisor

Attending, Division of Gastroenterology, Hepatology and Nutrition Senior Lecturer of Pediatrics, Harvard Medical School

Proudly Partnered

Our commitment to patient-centered innovation is driven by our partnerships with some of the leading healthcare organizations in the world. Eclipse Regenesis is proudly partnered with Boston Children’s Hospital, Cincinnati Children’s, UCLA Health, and Stanford Medicine. Together with our partners, we continue to pioneer the next generation of treatment for patients with Short Bowel Syndrome (SBS).

Join Us on the Path to Healing

Whether you’re a patient, clinician, or partner, there’s a place for you in the Eclipse journey. Get in touch or follow our updates as we reshape what’s possible in intestinal care.